Hello, My name is Brandon. Thanks for joining the Zoom Community! Go into your settings > audio > test mic/test speakers while in a screen share and see if your selected speaker and mic are still connected.
I would also do a reboot if this is happening because you could just have some corrupted files on your machine that need to be sorted. What operating system and Zoom version are you running on your machine?
If it is about the audio in your screen share, you should press the share audio button in a tablet. It seems counterintuitive, but you should see the button as 'off'.